Kinase activity and subcellular distribution of a chimeric green fluorescent protein-tagged Janus kinase 2
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چکیده
منابع مشابه
Kinase activity and subcellular distribution of a chimeric green fluorescent protein-tagged Janus kinase 2.
Janus kinase 2 (JAK2) is an essential intracellular signal transducer for numerous cytokines and hormones. To examine how JAK2 structural modifications can affect cellular physiology, we created expression vectors for chimeric proteins containing an enhanced green fluorescent protein (EGFP) fused to rat JAK2 (EGFP/rJAK2), and a kinase-inactive variant, EGFP/rJAK2(K882E). The properties of EGFP/...
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ژورنال
عنوان ژورنال: Journal of Biomedical Science
سال: 2006
ISSN: 1021-7770,1423-0127
DOI: 10.1007/s11373-006-9111-9